Cell-Type-Specific Viral Recognition Simplex Virus Infection Is Controlled by Type I Interferon Production during Herpes
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چکیده
Published Ahead of Print 3 October 2007. 2007, 81(24):13315. DOI: 10.1128/JVI.01167-07. J. Virol. Søren R. Paludan Malmgaard, Nina Ank, Joel D. Baines, Zhijian J. Chen and Simon B. Rasmussen, Louise N. Sørensen, Lene Pathway, and Novel Recognition Systems Mitochondrial Antiviral Signaling Protein through Toll-Like Receptor 9, the Cell-Type-Specific Viral Recognition Simplex Virus Infection Is Controlled by Type I Interferon Production during Herpes
منابع مشابه
Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.
Recognition of viruses by germ line-encoded pattern recognition receptors of the innate immune system is essential for rapid production of type I interferon (IFN) and early antiviral defense. We investigated the mechanisms of viral recognition governing production of type I IFN during herpes simplex virus (HSV) infection. We show that early production of IFN in vivo is mediated through Toll-lik...
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تاریخ انتشار 2007